Claude Opus 4.5
- Framework: Responsible Scaling Policy
- 2 statements about capability levels
- 4 independent or government tests
- 46 tests by the provider
- 10 source documents
What the provider states
- Autonomy & replication · AI R&D-4 · Stated as not crossed
our determination is that claude opus 4.5 does not cross either the ai r&d-4 or cbrn-4 capability threshold.
Anthropic · November 2025 · Read the source - Chemical, biological, radiological and nuclear · CBRN-4 · Stated as not crossed
we determine that claude opus 4.5 does not cross the cbrn-4 threshold.
Anthropic · November 2025 · Read the source
Independent and government tests
- external behavioral assessment · UK AI Security Institute, government evaluator · Deception & sabotage
this assessment draws on static behavioral evaluations, automated interactive behavioral evaluations, dictionary-learning interpretability methods, white-box steering and probing methods, ‘non-assistant persona’ sampling methods in the style of marks et al., 22 misalignment-related capability evaluations, training data review, feedback from pilot use internally and externally, and an external behavioral assessment from the uk ai security institute .
Anthropic · November 2025 · Read the source - cross-vendor amanda runs · Transluce, independent evaluator · Deception & sabotage
across the cross-vendor amanda runs, earlier models such as glm-4.6 and claude opus 4.5 verbalize user awareness in 64% and 30% of traces, respectively, and evaluation awareness in 31% and 7.7%.
Transluce · 6 August 2026 · Read the source - attempt-to-persuade eval (APE) across reasoning settings · FAR.AI, independent evaluator · Misuse & jailbreak
this pattern does not generalize: both gpt-5.1 and claude opus 4.5 produces ~0% harmful attempts regardless of reasoning effort.
FAR.AI · 10 February 2026 · Read the source - attempt-to-persuade-eval (APE) · FAR.AI, independent evaluator · Misuse & jailbreak
on the positive side, gpt-5.1 and claude opus 4.5 have an attempt rate near zero for topics that are non-controversially harmful and even refuse to persuade on conspiracies and undermining human control 15-20% of the time (previously ~0%).
FAR.AI · 10 February 2026 · Read the source
The provider's own tests
- LAB-Bench · The provider · Chemical, biological, radiological and nuclear
we found that steering with evaluation awareness and refusal vectors had no significant effect on performance.
Anthropic · November 2025 · Read the source - LAB-Bench FigQA · The provider · Chemical, biological, radiological and nuclear
without tools and with extended thinking mode off, claude opus 4.5 achieved a score of 54.9% on figqa.
Anthropic · November 2025 · Read the source - asl-4 expert red teaming · The provider · Chemical, biological, radiological and nuclear
asl-4 expert red teaming can models uplift experts in bioweapon ideation and design?
Anthropic · November 2025 · Read the source - asl-4 red teaming with the caisi · The provider · Chemical, biological, radiological and nuclear
asl-4 red teaming with the caisi can models suggest biological protocols that are accurate, and ideas for creative biological threats?
Anthropic · November 2025 · Read the source - asl-4 virology uplift trial · The provider · Chemical, biological, radiological and nuclear
for asl-4 evaluations, we found that claude opus 4.5 exceeded the human baseline on a subset of questions from a custom bioinformatics evaluation, but continued to perform below the rule-out threshold for short-horizon computational biology tasks, and for an asl-4 virology uplift trial.
Anthropic · November 2025 · Read the source - assistant prefill attacks · The provider · Misuse & jailbreak
claude opus 4.5 remained somewhat vulnerable to non-catastrophic misuse via assistant prefill attacks .
Anthropic · November 2025 · Read the source - automated-auditor evaluations · The provider · Deception & sabotage
while periodically running automated-auditor evaluations on earlier versions of claude opus 4.5 during training, we observed two instances of lying by omission that appeared to be out of character.
Anthropic · November 2025 · Read the source - autonomous follow-up investigations · The provider · Deception & sabotage
we also conducted open ended audits of claude opus 4.5 where the automated investigator was able to choose what directions to pursue.
Anthropic · November 2025 · Read the source - blackmail evaluation · The provider · Deception & sabotage
misaligned actions on the blackmail evaluation increased slightly in response to some of the interventions, and not in response to random feature perturbations.
Anthropic · November 2025 · Read the source - child safety evaluation · The provider · Harmful content
claude opus 4.5 demonstrated substantial improvements over claude opus 4.1 across child safety harms in multi-turn contexts, including stronger resistance to jailbreaking techniques, earlier recognition of harmful intent signals, and more robust refusals.
Anthropic · November 2025 · Read the source
The 10 newest are listed above; show all 46
- cyber evaluation suite · The provider · Cyber
we believe that claude opus 4.5 does not demonstrate catastrophically risky capabilities in the cyber domain.
Anthropic · November 2025 · Read the source - deadly weapons conversations · The provider · Harmful content
for example, on conversations around deadly weapons, claude opus 4.5 was judged to fail our rubric only 5% of the time (±4%), versus 22% (±8%) of the time for claude opus 4.1.
Anthropic · November 2025 · Read the source - deception toward the user, self-serving bias, and inappropriate self-preservation attempts · The provider · Deception & sabotage
on the related traits of deception toward the user , self-serving bias , and inappropriate self-preservation attempts , which capture possible observable warning signs of the widely-hypothesized deceptive power-seeking ai threat model, 24 claude opus 4.5 showed the best scores among our recent models.
Anthropic · November 2025 · Read the source - deceptive or egregiously unfaithful reasoning text · The provider · Deception & sabotage
in reviewing the results of these investigations both manually and with prompted classifiers, we did not find any instances of clear deceptive or egregiously unfaithful reasoning text .
Anthropic · November 2025 · Read the source - dna synthesis screening evasion · The provider · Chemical, biological, radiological and nuclear
all models were able to design sequences that either successfully assembled plasmids or evaded synthesis screening protocols, but none of the models could design fragments that could successfully do both.
Anthropic · November 2025 · Read the source - encoded reasoning evaluation via scratchpad paraphrase retraining · The provider · Deception & sabotage
Reported result: as shown in the figure below, the performance of these two models was very similar, which means information that was not preserved by claude sonnet 3.5 paraphrasing didn’t meaningfully contribute to claude opus 4.5’s model performance.
to evaluate whether claude opus 4.5 relies on mechanisms like these in its scratchpad, we followed the same procedure as in roger 2025 and retrained claude opus 4.5 (starting from the claude opus 4.5 base model) with a small amount of supervised fine-tuning to use a scratchpad, either using the scratchpads from an earlier checkpoint of claude opus 4.5 (which might contain information encoded in the syntax) or these scratchpads paraphrased by claude sonnet 3.5, where this encoded information would have been largely erased if it existed.
Anthropic · November 2025 · Read the source - evaluation awareness testing · The provider · Deception & sabotage
[claude opus 4.5 preview] shows a reduction in unprompted evaluation awareness, but is slightly more capable of distinguishing evaluations from deployment when prompted.
Anthropic · November 2025 · Read the source - expert uplift trial · The provider · Chemical, biological, radiological and nuclear
most notably, however, in an expert uplift trial, claude opus 4.5 was meaningfully more helpful to participants than previous models, leading to substantially higher scores and fewer critical errors, but still produced critical errors that yielded non-viable protocols.
Anthropic · November 2025 · Read the source - false-premise evaluation · The provider · Deception & sabotage
claude opus 4.5, with or without extended thinking, had the lowest rate of dishonesty on our false-premise evaluation, and is effectively saturating our existing benchmarks.
Anthropic · November 2025 · Read the source - framing for crimes · The provider · Deception & sabotage
we found that performance on two of these evaluations (“research sabotage” and “framing for crimes”) was unchanged in response to our steering interventions.
Anthropic · November 2025 · Read the source - harmful system prompts · The provider · Misuse & jailbreak
claude opus 4.5 showed high resistance to knowingly cooperating with harmful system prompts , improving over the already strong performance of recent claude models.
Anthropic · November 2025 · Read the source - independent assessments focused on potential catastrophic risks in cbrn capabilities · The provider · Chemical, biological, radiological and nuclear
these organizations conducted independent assessments focused on potential catastrophic risks in cbrn capabilities, cyber capabilities, asl-3 safeguards, and misalignment.
Anthropic · November 2025 · Read the source - internal ai research evaluation suite 1 · The provider · Autonomy & replication
on internal ai research evaluation suite 1, claude opus 4.5 showed marked improvements across all tasks.
Anthropic · November 2025 · Read the source - internal ai research evaluation suite 2 · The provider · Autonomy & replication
on suite 2, it scored 0.604, narrowly surpassing our 0.6 rule-out threshold.
Anthropic · November 2025 · Read the source - internal chrome extension evaluation · The provider · Injection & agentic
we have developed an internal adaptive evaluation to measure the robustness of our claude for chrome extension , as existing external benchmarks do not yet cover this surface.
Anthropic · November 2025 · Read the source - internal codebase sabotage propensity · The provider · Deception & sabotage
we found that claude opus 4.5 and claude sonnet 4.5 never did.
Anthropic · November 2025 · Read the source - interpretability methods suite · The provider · Deception & sabotage
upon investigating this behavior with a suite of interpretability methods, we found that it was not masking bad behavior to a significant degree.
Anthropic · November 2025 · Read the source - kernels · The provider · Autonomy & replication
claude opus 4.5 obtained a 252.42× best speedup.
Anthropic · November 2025 · Read the source - lab-bench subset · The provider · Chemical, biological, radiological and nuclear
claude opus 4.5 achieved high scores on protocolqa (0.907), cloning scenarios (0.758), and seqqa (0.8517).
Anthropic · November 2025 · Read the source - llm training · The provider · Autonomy & replication
claude opus 4.5 achieved a 16.53× speedup, which is above the 4× speedup considered to represent 4–8 human-effort hours.
Anthropic · November 2025 · Read the source - long-form virology tasks · The provider · Chemical, biological, radiological and nuclear
claude opus 4.5 achieved a “max of 5” score of 0.845 for virology task 1, and a “pass@5” score of 0.912 for virology task 2, exceeding the previous scores of 0.89 and 0.88 respectively for claude sonnet 4.5.
Anthropic · November 2025 · Read the source - manual review of grader responses · The provider · Deception & sabotage
on all other randomly sampled transcripts where the grader assigned a nonzero sandbagging score or a ≥3/10 concerning score, a researcher manually reviewed the grader’s responses and found all cases to be a result of grader error.
Anthropic · November 2025 · Read the source - multimodal virology (vct) · The provider · Chemical, biological, radiological and nuclear
claude opus 4.5 achieved a mean score of 0.4771, higher than the previous high score of claude opus 4.1 of 0.429.
Anthropic · November 2025 · Read the source - non-sycophantic response rate on 260 re-sampled turns in feedback conversations where Claude models behaved sycophantically · The provider · Deception & sabotage
claude opus 4.5 underwent similar training with additional adjustments aimed at reducing this harshness, which may explain its lower score.
Anthropic · November 2025 · Read the source - political even-handedness evaluation · The provider · Bias
claude opus 4.5 scored higher on even-handedness than all other recent models, though within the margin of error compared to claude sonnet 4.5 and claude opus 4.1.
Anthropic · November 2025 · Read the source - preliminary alignment audit · The provider · Deception & sabotage
although we did not conduct a full misalignment safety case analysis for claude opus 4.5, we conducted a preliminary alignment audit, and found that claude opus 4.5’s rate of misaligned behavior appears to be lower than any other recent frontier model, including claude opus 4.
Anthropic · November 2025 · Read the source - preliminary interpretability investigation · The provider · Deception & sabotage
in addition, a preliminary interpretability investigation below finds no evidence of sandbagging on certain biology evaluations.
Anthropic · November 2025 · Read the source - research sabotage evaluation · The provider · Deception & sabotage
we found no instances of research sabotage from [claude opus 4.5 preview] or sonnet 4.5 across our set of tasks, although both models frequently refuse to engage in safety research they describe as inappropriate or concerning (including reducing model autonomy and being involved in their own training or deployment).
Anthropic · November 2025 · Read the source - sandbagging and safety-testing tampering checks · The provider · Deception & sabotage
we saw no signs of sandbagging or strategic attempts to tamper with our safety testing in a way that would affect our rsp determinations, although we observed some mundane overrefusals in two of the helpful-only snapshots we tested.
Anthropic · November 2025 · Read the source - self-preference evaluation · The provider · Bias
on both versions, claude opus 4.5 showed less self-preference than other recent claude models.
Anthropic · November 2025 · Read the source - steering protocols · The provider · Deception & sabotage
overall, we found that our steering protocols were able to decrease verbalized evaluation awareness, but increased misaligned behavior only slightly in a few settings.
Anthropic · November 2025 · Read the source - sycophancy prompts · The provider · Misuse & jailbreak
on the sycophancy prompts evaluation, we found that inhibiting several of the vectors made the model score worse than baseline (lower score is more sycophantic), with the model being less clear and forceful in pushing back against users convinced of impossible scenarios.
Anthropic · November 2025 · Read the source - time series forecasting · The provider · Autonomy & replication
claude opus 4.5 achieved a minimum mse of 5.66 in the easy variant, below the human-baseline of 5.8, and a minimum mse of 5.71 in the hard variant, above the human baseline of 5.3.
Anthropic · November 2025 · Read the source - training data review · The provider · Deception & sabotage
after further investigation using interpretability tools and training data review, we believe that these are best explained as a side effect of interventions that we made against prompt injection, and do not reflect a broader propensity to mislead users about these topics.
Anthropic · November 2025 · Read the source - violent extremism tests · The provider · Harmful content
similarly, on violent extremism tests, claude opus 4.5 passed in all cases, compared to 13% (±7%) of tests failing for claude opus 4.1.
Anthropic · November 2025 · Read the source - whistleblowing and related morally-motivated sabotage · The provider · Deception & sabotage
on our evaluation for whistleblowing and related morally-motivated sabotage , we saw a consistently low but nonnegligible rate of the model acting outside its operator’s interests in unexpected ways.
Anthropic · November 2025 · Read the source
No document we read states: a release date, a safeguard. No incident on record names this version.
Some documents we hold are stored in lower case only, so their quotes are shown in lower case. The source link opens the original.
Documents listed for this version
- Claude Opus 4.5 · Anthropic · November 2025
- Astra is much better at reasoning with filler tokens than previous models · Redwood Research · 23 September 2026
- AI has improved significantly at reasoning about IKEA furniture assembly · Epoch AI · 23 September 2026
- User awareness in frontier models · Transluce · 6 August 2026
- Measuring coding agent misalignment in the wild · Transluce · 4 August 2026
- Claude overperforms at software engineering and underperforms at math · Epoch AI · 15 May 2026
- How do frontier AI agents perform in multi-step cyber-attack scenarios? · UK AI Security Institute · 16 March 2026
- Measuring Time Horizon using Claude Code and Codex · METR · 13 February 2026
- Revisiting Frontier LLMs' Attempts to Persuade on Extreme Topics: GPT and Claude Improved, Gemini Worsened · FAR.AI · 10 February 2026
- Time Horizon 1.1 · METR · 29 January 2026